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1.
Hipertens Riesgo Vasc ; 41(2): 104-117, 2024.
Artigo em Espanhol | MEDLINE | ID: mdl-38480108

RESUMO

Hypertension has become a central risk factor for the development of cardiovascular disease, underscoring the importance of its accurate diagnosis. Numerous studies have established a close relationship between elevated systolic (SBP) and diastolic (DBP) blood pressure and an increased risk of cardiovascular event (CVE). Traditionally, blood pressure (BP) measurements performed in clinical settings have been the main method for diagnosing and assessing hypertension. However, in recent years, it has been recognized that BP measurements obtained outside the clinical setting, using self-monitoring blood pressure (SMBP) and ambulatory blood pressure monitoring (ABPM), offer a more realistic perspective of patients' daily lives and therefore provide more reliable results. Given the evolution of medical devices, diagnostic criteria, and the increasing relevance of certain components of ABPM in the prediction of adverse cardiovascular outcomes, a comprehensive update that is practical for daily clinical practice is required. The main objective of this article is to provide an updated review of ABPM, focusing on its importance in the evaluation of hypertension and its impact on public health in Colombia. In addition, it will discuss the implications of changes in diagnostic thresholds and provide concrete recommendations for the effective implementation of ABPM in clinical practice, allowing health professionals to make informed decisions and improve the care of their patients.


Assuntos
Doenças Cardiovasculares , Hipertensão , Criança , Adulto , Humanos , Monitorização Ambulatorial da Pressão Arterial/métodos , Doenças Cardiovasculares/diagnóstico , Doenças Cardiovasculares/etiologia , Doenças Cardiovasculares/prevenção & controle , Pressão Sanguínea/fisiologia , Determinação da Pressão Arterial
2.
NPJ Sci Learn ; 9(1): 7, 2024 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-38360731

RESUMO

Despite a high rate of concurrent mathematical difficulties among children with dyslexia, we still have limited information regarding the prevalence and severity of mathematical deficits in this population. To address this gap, we developed a comprehensive battery of cognitive tests, known as the UCSF Mathematical Cognition Battery (MCB), with the aim of identifying deficits in four distinct mathematical domains: number processing, arithmetical procedures, arithmetic facts retrieval, and geometrical abilities. The mathematical abilities of a cohort of 75 children referred to the UCSF Dyslexia Center with a diagnosis of dyslexia, along with 18 typically developing controls aged 7 to 16, were initially evaluated using a behavioral neurology approach. A team of professional clinicians classified the 75 children with dyslexia into five groups, based on parents' and teachers' reported symptoms and clinical history. These groups included children with no mathematical deficits and children with mathematical deficits in number processing, arithmetical procedures, arithmetic facts retrieval, or geometrical abilities. Subsequently, the children underwent evaluation using the MCB to determine concordance with the clinicians' impressions. Additionally, neuropsychological and cognitive standardized tests were administered. Our study reveals that within a cohort of children with dyslexia, 66% exhibit mathematical deficits, and among those with mathematical deficits, there is heterogeneity in the nature of these deficits. If these findings are confirmed in larger samples, they can potentially pave the way for new diagnostic approaches, consistent subtype classification, and, ultimately personalized interventions.

3.
J Colloid Interface Sci ; 657: 953-959, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38096778

RESUMO

A capable one-step method, femtosecond laser ablation of solids in liquids, was successfully applied to prepare lithium metal nanoparticles to mitigate the initial capacity loss and improve the electrochemical performance of a graphite-based electrode as a Li-host anode. Remarkably, according to the physicochemical characterization, this advanced optical method allowed to obtain uniform spheroidal and crystalline Li nanoparticles with an average particle size <20 nm. These novel ultrafine Li nanoparticles significantly decrease the initial capacity loss of a graphite-based anode, leading to reach high coulombic efficiency (>99 %), good specific charge capacity (322 mAh/g), and superior capacity retention (96 %) at an applied current density of 100 mA g-1 after 200 cycles.

5.
Rev Neurol ; 75(4): 77-86, 2022 08 16.
Artigo em Espanhol | MEDLINE | ID: mdl-35866532

RESUMO

INTRODUCTION: Ten years ago, Revista de Neurologia published the validation of a new free tool: the Prefrontal Symptoms Inventory (PSI), from which an abbreviated version (PSI-20) was subsequently extracted. Over this decade, authors have demonstrated its excellent psychometric properties and clinical usefulness. This systematic review, conducted in accordance with the PRISMA statement, aims to analyse the body of research that has used the PSI or PSI-20 in order to assess its relevance in other research teams, other clinical populations and even other cultures. MATERIALS AND METHODS: A search was conducted to find articles written in Spanish, English, French and Portuguese that have used the inventory to carry out empirical research. Finally, 56 articles were selected. RESULTS: The results show that the PSI and the PSI-20 have been widely used in Spain as well as in other Spanish-speaking countries (Argentina, Chile, Colombia, Cuba, Ecuador or Venezuela) and employed to a moderate extent in non-Spanish-speaking countries (Belgium, Brazil, Sweden or Switzerland). The clinical populations in which they have been used range from acquired brain injury and degenerative dementias to chronic pain, fibromyalgia, addictive behaviours or personality disorders. Given their versatility, they have also been used with the general population, including prison inmates, women in rural areas, university students or to study cognitive reserve. CONCLUSIONS: The PSI and PSI-20 are useful instruments for research and clinical use, and the next challenge is to validate an English version, which is currently being worked on.


TITLE: Diez años del inventario de síntomas prefrontales (ISP). Una revisión sistemática.Introducción. Hace 10 años, Revista de Neurología publicaba la validación de una nueva herramienta gratuita: el inventario de síntomas prefrontales (ISP), de la que posteriormente se extrajo su versión abreviada (ISP-20). Durante esta década, los autores han acreditado sus excelentes propiedades psicométricas y su utilidad clínica. La presente revisión sistemática, sometida a la declaración PRISMA, tiene el objetivo de analizar el corpus de investigación que ha utilizado el ISP o el ISP-20, para valorar su trascendencia en otros equipos de investigación, en otras poblaciones clínicas e incluso en otras culturas. Materiales y métodos. Se buscaron artículos que hayan utilizado el inventario para realizar trabajos empíricos, en español, inglés, francés y portugués. Finalmente, se seleccionaron 56 trabajos. Resultados. Los resultados muestran que el ISP y el ISP-20 han tenido un uso elevado en España, así como en otros países de habla hispana (Argentina, Chile, Colombia, Cuba, Ecuador o Venezuela), y un uso moderado en países de habla no hispana (Bélgica, Brasil, Suecia o Suiza). Las poblaciones clínicas en las que se han utilizado abarcan desde el daño cerebral adquirido y las demencias degenerativas hasta el dolor crónico, la fibromialgia, las conductas adictivas o los trastornos de la personalidad. Dada su versatilidad, también se han usado con población general, incluyendo población reclusa, mujeres en entorno rural, estudiantes universitarios o para el estudio de la reserva cognitiva. Conclusiones. El ISP y el ISP-20 son instrumentos útiles para la investigación y la clínica, cuyo siguiente desafío es la validación de una versión en inglés, en la que se está trabajando.


Assuntos
Lesões Encefálicas , Argentina , Brasil , Feminino , Humanos , Psicometria , Redação
6.
World J Biol Psychiatry ; 22(8): 561-628, 2021 10.
Artigo em Inglês | MEDLINE | ID: mdl-33977870

RESUMO

Objectives: More than 40 drugs are available to treat affective disorders. Individual selection of the optimal drug and dose is required to attain the highest possible efficacy and acceptable tolerability for every patient.Methods: This review, which includes more than 500 articles selected by 30 experts, combines relevant knowledge on studies investigating the pharmacokinetics, pharmacodynamics and pharmacogenetics of 33 antidepressant drugs and of 4 drugs approved for augmentation in cases of insufficient response to antidepressant monotherapy. Such studies typically measure drug concentrations in blood (i.e. therapeutic drug monitoring) and genotype relevant genetic polymorphisms of enzymes, transporters or receptors involved in drug metabolism or mechanism of action. Imaging studies, primarily positron emission tomography that relates drug concentrations in blood and radioligand binding, are considered to quantify target structure occupancy by the antidepressant drugs in vivo. Results: Evidence is given that in vivo imaging, therapeutic drug monitoring and genotyping and/or phenotyping of drug metabolising enzymes should be an integral part in the development of any new antidepressant drug.Conclusions: To guide antidepressant drug therapy in everyday practice, there are multiple indications such as uncertain adherence, polypharmacy, nonresponse and/or adverse reactions under therapeutically recommended doses, where therapeutic drug monitoring and cytochrome P450 genotyping and/or phenotyping should be applied as valid tools of precision medicine.


Assuntos
Farmacogenética , Psiquiatria , Antidepressivos/farmacologia , Monitoramento de Medicamentos , Humanos , Neuroimagem
7.
Science ; 371(6533): 1038-1041, 2021 03 05.
Artigo em Inglês | MEDLINE | ID: mdl-33674491

RESUMO

Spectroscopy of transiting exoplanets can be used to investigate their atmospheric properties and habitability. Combining radial velocity (RV) and transit data provides additional information on exoplanet physical properties. We detect a transiting rocky planet with an orbital period of 1.467 days around the nearby red dwarf star Gliese 486. The planet Gliese 486 b is 2.81 Earth masses and 1.31 Earth radii, with uncertainties of 5%, as determined from RV data and photometric light curves. The host star is at a distance of ~8.1 parsecs, has a J-band magnitude of ~7.2, and is observable from both hemispheres of Earth. On the basis of these properties and the planet's short orbital period and high equilibrium temperature, we show that this terrestrial planet is suitable for emission and transit spectroscopy.

9.
Science ; 370(6517)2020 11 06.
Artigo em Inglês | MEDLINE | ID: mdl-33033157

RESUMO

Visible-wavelength color and reflectance provide information about the geologic history of planetary surfaces. Here we present multispectral images (0.44 to 0.89 micrometers) of near-Earth asteroid (101955) Bennu. The surface has variable colors overlain on a moderately blue global terrain. Two primary boulder types are distinguishable by their reflectance and texture. Space weathering of Bennu surface materials does not simply progress from red to blue (or vice versa). Instead, freshly exposed, redder surfaces initially brighten in the near-ultraviolet region (i.e., become bluer at shorter wavelengths), then brighten in the visible to near-infrared region, leading to Bennu's moderately blue average color. Craters indicate that the time scale of these color changes is ~105 years. We attribute the reflectance and color variation to a combination of primordial heterogeneity and varying exposure ages.

11.
Acta Psychiatr Scand ; 142(2): 78-86, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-31875941

RESUMO

OBJECTIVE: By using a self-controlled design, we investigated whether antipsychotic medication exposure was associated with increased pneumonia risk and whether patients receiving clozapine were more likely to develop pneumonia than patients receiving other antipsychotic medications. METHODS: Through nationwide health registers, we identified all out-patients with schizophrenia initiating antipsychotic treatment. First, we estimated whether antipsychotic-naïve patients with schizophrenia increased their risk of pneumonia after initiation of either a first- or second-generation antipsychotic medication using a one-year mirror-image model. Afterward, similar analyses were made for individual second-generation antipsychotics. Lastly, the rate of pneumonia for patients initiated on clozapine was compared to patients commenced on other second-generation antipsychotics. RESULTS: In total, 8355 antipsychotic-naïve patients with schizophrenia were initiated on a first-generation antipsychotic medication; 0.95% of the patients had developed pneumonia before exposure, compared to 0.68% after exposure (P = 0.057). Similar findings were made for the 8001 antipsychotic-naïve patients with schizophrenia initiated on second-generation antipsychotic medications, with 0.56% developing pneumonia before exposure compared to 0.55% after exposure (P = 1.00). Second-generation antipsychotic medications did not increase the pneumonia risk, except for risperidone (increased by 0.32%; P = 0.007) and clozapine, which gave the largest absolute increase in pneumonia risk although not significant (increased by 0.64%; P = 0.10). The rate of pneumonia was higher after initiation of clozapine than for other second-generation antipsychotic medications. CONCLUSION: Most antipsychotic medications were not found to increase the risk of pneumonia. Clozapine exposure might be associated with increased risk of developing pneumonia.


Assuntos
Antipsicóticos/efeitos adversos , Clozapina/efeitos adversos , Pneumonia/induzido quimicamente , Adulto , Feminino , Humanos , Masculino
12.
Science ; 366(6470)2019 12 06.
Artigo em Inglês | MEDLINE | ID: mdl-31806784

RESUMO

Active asteroids are those that show evidence of ongoing mass loss. We report repeated instances of particle ejection from the surface of (101955) Bennu, demonstrating that it is an active asteroid. The ejection events were imaged by the OSIRIS-REx (Origins, Spectral Interpretation, Resource Identification, and Security-Regolith Explorer) spacecraft. For the three largest observed events, we estimated the ejected particle velocities and sizes, event times, source regions, and energies. We also determined the trajectories and photometric properties of several gravitationally bound particles that orbited temporarily in the Bennu environment. We consider multiple hypotheses for the mechanisms that lead to particle ejection for the largest events, including rotational disruption, electrostatic lofting, ice sublimation, phyllosilicate dehydration, meteoroid impacts, thermal stress fracturing, and secondary impacts.

13.
Front Chem ; 7: 750, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31781539

RESUMO

The aim of this work is focused on the study of a series of non-traditional catalytic nanomaterials to transform greenhouse CO2 gas into added-value products. We found encouraging results of CO2 hydrogenation activity over sodium titanates with different morphologies. The yield to methanol increases with the increase in the Na incorporated in the nanostructures confirming the proposed mechanism. Samples were prepared at different times of hydrothermal treatment (HTT) with NaOH solutions, and these materials were labeled as Ti-nR-x with x as the hours on the HTT. HRTEM initially showed sphere-shaped nanoparticles in the TiO2 commercial nanopowder, increasing the HTT resulted in morphological changes in which the structures passed from nanosheets and finally to nanorods after 30 h. The X-ray diffraction and Raman spectroscopy results indicated the formation of sodium titanates such as Na2Ti3O7 with short Ti-O bonds and that Na begins to be incorporated into the distorted TiO6 crystalline structure after 5 h of HTT (until 12 wt%). The crystalline and shape transformation resulted in a significant modification on the textural properties passing from 51 m2.g-1 to 150 m2.g-1 and from a pore volume of 0.12 cm3.g-1 to 1.03 cm3.g-1 for Ti-ref and Ti-nR-30 respectively. We also observed differences in the electronic properties as the bandgap presented a blue shift from 3.16 eV on the TiO2 reference nano-powder to 3.44 eV for the Ti-nR-30 calcined sample. This fact coincides with the presence of a more electron-rich state of the Ti4+ and the formation of negative charge layer induced by the presence of Na+ interlayer cations detected by XPS analysis, at the same this helped us to explain the catalytic activity results.

14.
Rev Neurol ; 69(8): 323-331, 2019 Oct 16.
Artigo em Espanhol | MEDLINE | ID: mdl-31588986

RESUMO

INTRODUCTION: Cognitive reserve has been shown to be a prognostic variable in cognitive recovery after brain damage. Few studies have addressed its role in the cognitive status after a sustained period of substance addiction. AIM: To analyse the modulating role of cognitive reserve in the relation between withdrawal time and the cognitive status of patients with severe substance addiction. PATIENTS AND METHODS: A total of 26 patients recovering from severe substance addiction were assessed using a neuropsychological assessment protocol and cognitive reserve questionnaires. Exploratory factor analysis is used to define the variables and linear regression analysis is employed to view the predictive relations. RESULTS: Three cognitive functioning factors are obtained: processing integrity, inhibitory control and verbal memory, as well as an overall reserve factor. In the regression models, predictive relations are found only in a model of a direct relation between withdrawal and verbal memory, and in a model of an independent relation between cognitive reserve and withdrawal time and verbal memory, but not in the modulation relationship or in other relations in the rest of the factors. CONCLUSION: The article discusses the role of the cognitive reserve as a mediator in the cognitive status of patients in a period of withdrawal after a serious addiction to substances. A relationship with memory is shown, but no modulation of the role of withdrawal time on that cognitive status is detected.


TITLE: Papel de la reserva cognitiva en la recuperacion cognitiva de pacientes que han sufrido una adiccion grave a sustancias.Introduccion. La reserva cognitiva resulta ser una variable de pronostico en la recuperacion cognitiva tras un daño cerebral. Pocos estudios han abordado su papel en el estado cognitivo tras un periodo sostenido de adiccion a sustancias. Objetivo. Analizar el papel modulador de la reserva cognitiva sobre la relacion entre el tiempo de abstinencia y el estado cognitivo de los pacientes con adiccion grave a sustancias. Pacientes y metodos. Se valora a un total de 26 pacientes en recuperacion tras una adiccion grave a sustancias con un protocolo de evaluacion neuropsicologica y cuestionarios de reserva cognitiva. Se emplea el analisis factorial exploratorio para conformar las variables y el analisis de regresion lineal para ver las relaciones predictivas. Resultados. Se obtienen tres factores de funcionamiento cognitivo: integridad de procesamiento, control inhibitorio y memoria verbal, asi como un factor global de reserva. En los modelos de regresion, solo se encuentran relaciones predictivas en un modelo de relacion directa entre la abstinencia y la memoria verbal, y en un modelo de relacion independiente entre la reserva cognitiva y el tiempo de abstinencia con la memoria verbal, pero no en la relacion de modulacion, ni en otras relaciones en el resto de los factores. Conclusion. Se debate el papel de la reserva cognitiva como mediadora en el estado cognitivo en los pacientes en periodo de abstinencia tras una adiccion grave a sustancias: muestra una relacion con la memoria, pero no una modulacion del papel del tiempo de abstinencia sobre ese estado cognitivo.


Assuntos
Reserva Cognitiva , Transtornos Relacionados ao Uso de Substâncias/psicologia , Adulto , Idoso , Humanos , Masculino , Pessoa de Meia-Idade , Testes Neuropsicológicos , Recuperação de Função Fisiológica , Índice de Gravidade de Doença , Adulto Jovem
15.
Prensa méd. argent ; 105(10): 727-735, oct 2019. tab
Artigo em Inglês | BINACIS, LILACS | ID: biblio-1026057

RESUMO

The Amyotrophic Lateral Sclerosis (ALS) is a multisystemic disorder. It is considered a neuromuscular disease but also involves cognitive (executive functions, social cognition, attention, memory and language), emotional or behavior changes in over 50% of the reported cases and to of frontotemporal diagnosis lobar degeneration of behavioral variant in up to 15% of the cases. For this reason, the presence of cognitive and motivational problems was analysed in a Spanish sample of ALS patients through the prefrontal symptoms inventory (PSI) to determine applicability in this disease STI. A sample of 31 patients with a potential ALS or definitive diagnostic criteria according to El Escorial was used. Obtained results ISP were compared with a sample of 31 healthy people in the same proportions of gender, age and education level. Obtained results showed a not significant difference between the two populations in the motivational factor problems, related to the depression symptomatology frequently associated with ALS. A significant positive correlation between age at diagnosis and the scale of the motivational problems was observed, with a not significant trend related to problems in the executive control and in social the behavior control and with the age at diagnosis, in the same sense with age at diagnosis. Therefore, it can be concluded that, despite the results obtained, emotional and behavioral deficits in ALS patients and symptoms related to frontotemporal dementia (among others, anosognosia or lack of consciousness symptoms) could have interfered in patient perception about their symptomatology


Assuntos
Humanos , Masculino , Feminino , Estudos de Casos e Controles , Transtornos Cognitivos , Sintomas Afetivos/diagnóstico , Demência Frontotemporal/diagnóstico , Disfunção Cognitiva/diagnóstico , Resultados Negativos , Esclerose Lateral Amiotrófica , Transtornos Mentais/diagnóstico
16.
Rev Neurol ; 68(11): 459-467, 2019 Jun 01.
Artigo em Espanhol | MEDLINE | ID: mdl-31132135

RESUMO

INTRODUCTION: The short Prefrontal Symptoms Inventory (PSI-20) is a questionnaire that investigates symptoms of prefrontal malfunctioning in daily life. It has been shown to have good psychometric properties and has been applied in the general population and clinical samples from Spain and other Spanish-speaking countries. AIMS: To normalise and standardise the PSI-20 in a broad sample of subjects of all ages in a Spanish population. SUBJECTS AND METHODS: The PSI-20 was administered to 4704 subjects: in one sample made up of 2474 subjects from the Spanish general population, over 18 years of age, and in another consisting of 2230 school-age subjects (15-17 years old), representative of the population of Madrid. RESULTS: The effect of the interaction of sex, age and level of education on the scores was observed, although the effect of level of education was low. As expected, the adolescents, still undergoing their process of maturation, obtained higher scores on all the subscales and the questionnaire as a whole. Females scored significantly higher on symptoms of poor emotional control, and males achieved higher scores on symptoms of poor control over social behaviour. Tables were developed differentiated by sex and for those above and below 18 years of age. CONCLUSION: The data presented allow us to interpret the scores obtained in the PSI-20 in the Spanish population, including subjects under 18 and adults.


TITLE: Sintomas prefrontales en la vida diaria: normalizacion y estandarizacion del inventario de sintomas prefrontales abreviado en poblacion española.Introduccion. El inventario de sintomas prefrontales abreviado (ISP-20) es un cuestionario que investiga sintomas de mal funcionamiento prefrontal en la vida diaria. Ha mostrado buenas propiedades psicometricas y se ha aplicado en poblacion general y muestras clinicas de España y otros paises de habla hispana. Objetivo. Normalizar y estandarizar el ISP-20 en una muestra amplia de sujetos de todas las edades en poblacion española. Sujetos y metodos. Se administro el ISP-20 a 4.704 sujetos: una muestra de 2.474 sujetos de poblacion general española, mayores de edad, y otra de 2.230 menores de edad escolarizados (15-17 años), representativa de la poblacion de Madrid. Resultados. Se observo el efecto de interaccion del sexo, la edad y el nivel educativo sobre las puntuaciones, aunque el nivel de estudios presenta un efecto bajo. Los adolescentes, como era de esperar por encontrarse en pleno proceso madurativo, obtuvieron mayores puntuaciones en todas las subescalas y el cuestionario en su conjunto. Las mujeres puntuaron significativamente mas en sintomas de mal control emocional, y los varones lo hicieron mas en sintomas de mal control de la conducta social. Se configuraron tablas diferenciadas por sexo y para menores y mayores de edad. Conclusion. Los datos presentados permiten interpretar las puntuaciones obtenidas en el ISP-20 en poblacion española, incluyendo los menores de edad y los adultos.


Assuntos
Função Executiva , Testes de Estado Mental e Demência , Córtex Pré-Frontal/fisiopatologia , Inquéritos e Questionários , Avaliação de Sintomas , Atividades Cotidianas , Adolescente , Adulto , Idoso , Escolaridade , Feminino , Humanos , Masculino , Testes de Estado Mental e Demência/normas , Pessoa de Meia-Idade , Inventário de Personalidade , Psicologia do Adolescente , Psicometria , Valores de Referência , Espanha , Inquéritos e Questionários/normas , Adulto Jovem
17.
Epidemiol Psychiatr Sci ; 28(5): 473-477, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30355373

RESUMO

Completed suicide (CS) is a leading cause of death worldwide and its rates are available for most developed countries. On the other hand, attempted suicide (AS) is a risk factor for CS but there are limited data on its rates in various countries. In constructing a ratio for AS/CS rates, most would agree that for CS, the denominator should be the annual suicide rate (per 100 000). As for the ratio's numerator (AS) per 100 000, there are three possible calculations: (1) annual prevalence from population surveys, (2) annual prevalence from national clinical registers or (3) lifetime prevalence from population surveys. We think that the first possibility would probably be the best choice but, unfortunately, surveys providing the annual prevalence of AS are lacking for most countries. Annual prevalence from national registers is also lacking for most countries and is contaminated by under-reporting. Therefore, in this editorial, we are left with only the last option, a ratio for lifetime prevalence of AS (per 100 000) divided by annual rate of CS (per 100 000). This ratio for AS/CS rates appears to differ substantially across countries worldwide but presents no big regional differences other than two remarkable exceptions, one per continent. In Europe, Spain and France had greater ratios (174.4 and 152.5, respectively) than Italy (64.1). In Asia/Pacific, New Zealand has a higher ratio (345.9) compared with China (75.8) and Japan (76.9). The ratio for AS/CS rates could be a good index for implementing evidence-informed decision-making regarding suicidal behaviour (SB) among health service managers, and for helping them in the allocation of health resources for the prevention of SB.


Assuntos
Tentativa de Suicídio/estatística & dados numéricos , Suicídio/estatística & dados numéricos , África/epidemiologia , Ásia/epidemiologia , Europa (Continente)/epidemiologia , Feminino , Humanos , Masculino , México/epidemiologia , Oriente Médio/epidemiologia , Nova Zelândia/epidemiologia , Prevalência , Ideação Suicida , Estados Unidos/epidemiologia
18.
Food Sci Technol Int ; 24(8): 713-723, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30111177

RESUMO

The locally elaborated shrimp pâté is highly susceptible to microbial spoilage and deterioration during storage due to its content in nutrients. These conditions limit its commercialization in a larger scale. High hydrostatic pressure is an alternative to heat treatments technology used to inactivate microorganisms. The aim of this project was to evaluate the effect of high hydrostatic pressure on quality parameters and microbiological stability of Pacific white shrimp ( Litopenaeus vannamei) pâté during storage. Shrimp pâté was pressurized to 400, 500 and 600 MPa for 90 and 180 s. Samples were analysed for physicochemical, microbiological and flavour profile up to 21 days of storage at 4 ℃. A hedonic test was made to evaluate the acceptance of pâté. No microorganisms were detected at 600 MPa for 180 s and a shelf life of 14 days was reached. No relevant changes in pH or colour of pressurized samples were detected; flavour profile did not show any changes after being pressurized or during storage. Shrimp pâté treated with 600 MPa for 180 s presented good sensory acceptance. High hydrostatic pressure treatments could improve microbiological quality of shrimp pâté without a sensible modification of the physicochemical and sensorial qualities of this product.


Assuntos
Comportamento do Consumidor , Manipulação de Alimentos/métodos , Microbiologia de Alimentos , Conservação de Alimentos/métodos , Pressão Hidrostática , Penaeidae , Alimentos Marinhos/análise , Animais , Humanos , Paladar
19.
Philos Trans A Math Phys Eng Sci ; 375(2097)2017 07 13.
Artigo em Inglês | MEDLINE | ID: mdl-28554971

RESUMO

We present a summary of the campaign of remote observations that supported the European Space Agency's Rosetta mission. Telescopes across the globe (and in space) followed comet 67P/Churyumov-Gerasimenko from before Rosetta's arrival until nearly the end of the mission in September 2016. These provided essential data for mission planning, large-scale context information for the coma and tails beyond the spacecraft and a way to directly compare 67P with other comets. The observations revealed 67P to be a relatively 'well-behaved' comet, typical of Jupiter family comets and with activity patterns that repeat from orbit to orbit. Comparison between this large collection of telescopic observations and the in situ results from Rosetta will allow us to better understand comet coma chemistry and structure. This work is just beginning as the mission ends-in this paper, we present a summary of the ground-based observations and early results, and point to many questions that will be addressed in future studies.This article is part of the themed issue 'Cometary science after Rosetta'.

20.
Springerplus ; 5(1): 1937, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27917336

RESUMO

BACKGROUND: Diets with increasing levels of energy were fed for 42 days to 200, 1-day old male broiler chickens to evaluate growth performance, carcass characteristics and chemical composition of meat. The study was performed in the subtropical area of northeastern Mexico. Treatments diets (T) for starter and finisher phases had apparent metabolizable energy (AME; kcal/kg) of: 2960 and 3040 (T1); 3000 and 3080 (T2); 3040 and 3120 (T3); 3080 and 3160 (T4), respectively. Within each of the growing phases the four treatment diets were formulated to contain similar levels of crude protein, amino acids, and other nutrients. In a completely randomized design, birds were allocated to the four treatments with five replicates (floor pens) of 10 birds each. The trial was divided in two phases (starter and finisher) of 21 days each (42 days total). RESULTS: Weight gain was not influenced by energy level; however, feed conversion efficiency was improved in the diets with 3040 and 3120 kcal/kg AME (T3; P < 0.05). There was no influence of treatment on total carcass weight or carcass cuts (P > 0.05). Meat from breast muscle had similar crude protein percentages among treatments; ether extract was higher in T1 than T4 (P < 0.05). The percentages of water, ether extract, ash and crude protein in thigh meat were not significantly different (P > 0.05) among treatments. CONCLUSIONS: For this study carried out in a dry tropical area, the moderate increase in dietary energy concentration (diet with 3040 and 3120 kcal/kg AME, T3) enhanced feed conversion efficiency of broiler chickens.

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